Tissue Intelligence System · Handheld Multi-Modal Sensing

See What
Tape Measures
Can't.

The Valvara Tissue Intelligence System (TIS) brings clinical-grade bioimpedance and tissue dielectric measurement to the point of care — objective tissue health intelligence in a single handheld scan.

DGFI
BIS Multi-ƒ
TDC Depth
DGFI Index
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3-in-1
BIS + TDC + DGFI Fusion
10M+
Americans with Lymphedema & Lymphatic Diseases
26+
Clinical Applications
4
Provisional Patent Families Filed

Objective tissue health.
At the point of care.

Clinicians managing lymphedema, post-surgical recovery, and chronic edema still rely on tape measures and subjective assessment — tools that miss subclinical changes until the window for early intervention has closed.

Valvara changes that. The Tissue Intelligence System (TIS) combines bioimpedance spectroscopy (BIS) and tissue dielectric constant (TDC) measurement into a single handheld scan, delivering our proprietary Depth-Gradient Fluid Index — quantitative tissue health data that enables earlier detection, smarter intervention, and measurable outcomes.

🩺

Clinical Precision

Combined BIS + TDC in a single handheld device — multi-frequency bioimpedance validated against gold-standard methods.

📊

Depth-Gradient Fluid Index

Our proprietary DGFI algorithm characterizes tissue fluid across depth layers — insight no single modality can provide alone.

Point-of-Care Workflow

Designed for the therapist's hands and the clinician's workflow — bringing objective tissue measurement to every visit, every patient.

🔬

Tissue Health Intelligence

Multi-modal sensing differentiates fluid compartments, tissue composition, and early pathological change.

The Platform

Multi-modal sensing.
One handheld wand.

01

Bioimpedance Spectroscopy (BIS)

Multi-frequency impedance measurement across a broad spectrum enables precise differentiation of extracellular and intracellular fluid compartments — the clinical gold standard for lymphedema quantification.

Core Measurement
02

Tissue Dielectric Constant (TDC)

Localized tissue water content measurement at controlled depths complements BIS with spatial resolution — together providing a complete picture of tissue fluid dynamics no single modality achieves alone.

Depth Profiling
03

Depth-Gradient Fluid Index

Valvara's proprietary DGFI algorithm fuses BIS and TDC data into a single composite index that characterizes tissue health across depth gradients — our core IP and clinical differentiator.

Proprietary Algorithm
04

Handheld Form Factor

A portable, clinician-owned wand that goes where the therapist goes — hospital, outpatient clinic, home visit, or satellite office. No floor-standing hardware. No hospital IT integration required.

Point of Care
05

Clinical Software Platform

Longitudinal trend visualization, anomaly flagging, and structured clinical reports give care teams actionable tissue health intelligence without adding workflow burden.

Software / SaaS
06

Multi-Modal Sensor Fusion

Integrated thermistors, pressure sensors, and contextual data enhance diagnostic accuracy and enable activity-adjusted, anatomically-aware tissue characterization.

Sensor Architecture

A new standard
for tissue measurement.

The clinicians treating lymphedema, post-surgical recovery, and chronic edema are working with tools built for a different era — or no objective tools at all. Valvara is building what tissue measurement should have been all along.

What Clinicians Face Today
  • Tape measures and subjective visual assessment as the default
  • Current tools locked to floor-standing hardware in one room
  • Single-modality data that misses depth and composition
  • Subclinical progression missed until symptoms are obvious
  • No objective metric that travels with the patient across settings
What Valvara Delivers
  • Quantitative, objective tissue health data at every visit
  • Handheld form factor — goes where the clinician goes
  • Multi-modal sensing: BIS + TDC fused into the proprietary DGFI
  • Early, subclinical change detection — not just end-stage confirmation
  • Platform architecture extensible across 26+ clinical indications

One platform.
26+ indications.

Valvara begins with lymphedema — the clearest clinical need and the most established bioimpedance evidence base. The platform is designed from day one to expand across conditions where tissue fluid dynamics and composition are clinically meaningful.

💧

Lymphedema

Primary indication · Early detection & staging

🧬

Lipedema

Adipose tissue differentiation · Disease monitoring

🏥

Post-Surgical

Recovery monitoring · Complication detection

❤️

Heart Failure

Fluid overload monitoring · Decompensation prediction

💪

Sarcopenia

Muscle mass tracking · Aging populations

👤

Head & Neck

Post-oncology lymphedema · Radiation sequelae

🤰

Preeclampsia

Maternal fluid surveillance · Risk stratification

+19 More

Expanding pipeline across oncology, nephrology & beyond

Platform expansion strategy covers 26+ clinical applications across 5 anatomical zones

Who We Serve
Certified Lymphedema Therapists
NAPBC-Accredited Breast Centers
Oncology Rehab Programs
Vascular & Wound Care Clinics
The Team

Clinical expertise
meets technical vision.

Valvara is co-founded by a clinical expert who has treated lymphedema patients firsthand and a technical founder building the IP, engineering, and business infrastructure to bring this to market.

VB

Valarie Bognanno

Co-Founder · Clinical Strategy

OTR/L, CLT-LANA. Certified lymphedema therapist with direct clinical experience treating the patients Valvara is built for. Drives clinical validation, customer discovery, and the go-to-market strategy rooted in real practitioner workflows.

TB

Tony Bognanno

Co-Founder · Technical & Business

Leads IP strategy, engineering partnerships, and business development. Architect of Valvara's patent portfolio spanning hardware, algorithms, clinical applications, and business methods.

Partnering with
mission-aligned
capital.

A pre-seed SAFE round is underway. We're selective about partners — looking for investors with conviction in medical devices, point-of-care diagnostics, and clinician-led companies. Reach out for terms, diligence materials, and a conversation.

Get in Touch

We review every inquiry personally. Submit below and we'll respond by email within 2 business days.

Prefer email? Reach us directly at investors@valvara.com